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Article: The Science of Ceramides: what are those?

The Science of Ceramides: what are those?

Understanding ceramides

Ceramides, wax-like lipid molecules, belong to a group of lipids or fats that make up two main components of our skin's cell membranes. Naturally present in the human skin, their levels decrease with age, essentially halting production by the age of 40 (1).

Why ceramides matter?

Ceramides are essential for maintaining healthy skin of all genders and skin types and are beneficial for everyone, regardless of skin concerns. Ceramides play an important role in strengthening the skin barrier, preventing moisture loss and protecting against environmental aggressors (2).  Using ceramide-enriched skin care products is essential to combat dryness, flakiness, and maintain a supple complexion.

Especially in the cold embrace of the winter, our skin faces significant decrease in ceramides level, as depicted in the graph illustrating seasonal effects on ceramide levels in human skin. Ceramides, vital lipid molecules for skin health, serve as the skin's natural protectors, forming a protective barrier against harsh weather conditions. In winter, this protective shield weakens, making the skin more sensitive to dryness and external stress factors.


Source of the diagram: A.V.Rawlings, Skin Barrier (2006), "Sources and Role of Stratum Corneum Hydration", 399-425.

The importance of the ratio of occlusive ingredients to skin lipids

Pay attention to the occlusive ingredients in the moisturizer - especially if you have dry skin or it shows signs of aging - for example, natural occlusive ingredients like lanolin, or synthetic ones like petrolatum and dimethicone, as well as possible microplastics (like acrylates). If they are combined with ceramides in a product, it is important to check that the 3:1:1 ratio of skin lipids to ceramides, free fatty acids and cholesterol is maintained. Without this balance, the product might lead to a disrupted skin barrier, potentially causing increased dependency on these products and exacerbating skin problems over time (4).


What are the benefits of ceramides for the skin barrier?

  • Moisture Retention: Prevents moisture loss, keeping skin hydrated, smooth and supple.
  • Protective layer: forms a barrier that protects the skin from dehydration and environmental damage.
  • Anti-aging: Promotes anti-aging by keeping skin moist and supple (3).


Skin care product with ceramides

We, the LABRAINS team, truly care about how your skin feels, and as a team of chemists we understand what works for skin and overall health in the long term. Therefore LABRAINS offers a range of skin care products enriched with ceramides to address different skin needs:

  1. Oil-to-Milk face cleansing oil-milk
  2. Renovation Sculptor cream
  3. Night Restoration Architect night cream
  4. ABC deeply nourishing cream
  5. Dermatreat skin rejuvenating cream
  6. BB cream

By including these nourishing products in your daily routine, you will provide your skin with the care it deserves, especially in the cold and dry weather. Discover the secret to healthier, more elastic facial skin with LABRAINS.


Scientific references:

  1. Arawwawala, M., & Thabrew, I. (2017). In vivo and in vitro analysis of the cosmetic and medicinal potentials of Sri Lankan green tea. Current Bioactive Compounds, 13(4), 272–280. doi: 10.2174/1573407213666170209155941.
  2. Spada, F., Barnes, T. M., & Greive, K. A. (2018). Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems. Clinical, Cosmetic and Investigational Dermatology, 11, 491–497. doi: 10.2147/CCID.S177697.
  3. Lee, B., & Jang, S. (2019). The Role of Ceramides in Skin Health and Their Use in Dermatology. Journal of Cosmetic Dermatology.
  4. Peter M. Elias (2022). Optimizing emollient therapy for skin barrier repair in atopic dermatitis. Journal of Science, 128(5).

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